Multiple plasma samples were drawn on day 1 and day 7 of the trial and once daily during the washout period after the final dose. During phases I and II, subjects received the conventional oral dosage form of clonazepam, 0.5 mg 3 times daily, for 7 days. Nine healthy volunteers participated in a 3-phase clinical pharmacokinetic study of the benzodiazepine derivative clonazepam.
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